HUBUNGAN KADAR KARBOKSIHEMOGLOBIN (Hb-CO) TERHADAP KADAR HEMOGLOBIN (Hb) DAN KADAR HEMATOKRIT (PCV) PADA PEROKOK AKTIF

Abstract

Smoking is the main source of monoxide carbon (CO) exposure. CO would bond with hemoglobin
to form carboxyhemoglobin compound (HbCO). When CO bonds with hemoglobin, CO gas would
occupy the O2 place inside hemoglobin thereby the body accelerateeritropoietic process that would
boost erythrocyte production and hemoglobin concentration as the result of the low of O2parsial
pressure inside the body. These erythrocyte increase has the positive correlation to hematocrit
level. The goal of this research goal was to find out the correlation between HbCO concentration
with hemoglobin and hematocrit concentration.
This research was conductes on May – June 2016 with 20 active smoker men in RW 004 and RW
005 KelurahanBongkaranKecamatanPabeanCantikan Surabaya, selected with purposive sampling.
Method of this research was analytical survey with cross sectional approximation and performed in
3 laboratories that were BBLK Surabaya laboratory for HbCO examination,
LaboratoriumTerpaduPoliteknikKesehatan Surabaya for hemoglobin examination, and Hematology
Laboratory AnalisKesehatan Surabaya for hematocrit examination.
The result of this research showed the average HbCO content was 8.86 %; hemoglobin content
was 15.01 g/dL; an hematocrit content was 45.95%. The determination of correlation between
HbCO concentration with hemoglobin and hematocrit concentration was held with Pearson
Correlation Test. The final result indicated the presence of correlation between HbCO concentration
and hemoglobin concentration on active smoker (sig < 0.01) with strong correlation (r = 0.783)
and there also was correlation of HbCO concentration with hematocrit concentration on active
smoker (sig. < 0.05) with moderate correlation (r = 0.539).