PENGARUH INFUSA KAYU SECANG (Caesalpinia sappan L.) TERHADAP KEMATIAN CACING Ascaris suum, Goeze IN VITRO

Abstract

Ascariasis is a parasitic disease caused by the nematode Ascaris lumbricoides. Ascariasis can be treated with
deworming. Deworming drugs (anthelmintics) synthetic can cause symptoms such as nausea, vomiting and
diarrhea. One of the traditional plants that are useful for deworming is the sappan wood plant (Caeselpinia
sappan. L). Secang wood contains flavonoids, saponins, alkaloids, tannins, phenolic compounds, triterpenoids
and glycosides. It turns out that there is a relationship between the content of flavonoids and tannins with the
death of Ascaris suum, so that the development of Secang Wood can be used to be developed, researched and
proven as an alternative herbal medicine to develop medicine in Indonesia. This type of research is an
experimental study, which was conducted from February to May 2019 at the Parasitology Laboratory of the
Health Analyst Department of the Health Polytechnic of the Ministry of Health Surabaya. The statistical test
used is the One Way Annova test. Based on the results of the study, the results of the infusion of sappan wood
(Caesalpinia sappan L) at each concentration of 10%, 20%, 30% and 40% had an average death time of
Ascaris suum Goeze worms for 436 minutes at a concentration of 10%, a concentration of 20% the average time
of death was 373 minutes, the concentration of 30% obtained the average time of death for 317 minutes, the
concentration of 40% with the average time of death was 255 minutes. Positive control had an average worm
death time of 86 minutes and negative control had an average worm death time of 5673 minutes. Thus, it can be
concluded that the higher the concentration of sappan wood infusion, the faster the required worm death time.
Keywords : Secang wood (Caesalpinia sappan L); Ascaris suum Goeze worm; Worm death time